Avci C, Ozmen V, Avtan L, Buyukuncu Y, Muslumanoglu M
Department of Surgery, Istanbul Medical Faculty, Istanbul University, Turkey.
Hepatogastroenterology. 1999 May-Jun;46(27):1494-9.
BACKGROUND/AIMS: This article describes the surgical techniques and preliminary results of a prospective trial of videoendoscopic bilateral truncal vagotomy without a drainage procedure in a series of selected patients with chronic non-obstructive intractible duodenal ulcer.
Video laparoscopic and videothoracoscopic truncal vagotomy of chronic duodenal ulcer in 32 patients has been successfully performed in the Department of Surgery, Istanbul Medical Faculty Hospital. These patients undergoing bilateral truncal vagotomy (BTV) without a drainage procedure were chosen with selective indication regarding the absence of pyloric obstruction and presence of hyperacidity. Endoscopic pyloric balloon dilatation (PBD) was performed at the same stage with vagotomy only for 20 patients as a prospective trial. The results of acid secretory tests and endoscopic control were studied.
All the patients tolerated pure truncal vagotomy well under strict follow-up with semiliquid diet and promotility medication started 24 hours after surgery. The mean decrease in secretory tests for basal acid output (BAO) and peak acid output (PAO) were 70.6% and 79.5%, respectively. Endoscopic controls, 2 months after the operation, showed healing ulcers in patients who were able to be followed-up. One patient who had partial pyloric stenosis and was operated by BTV and PBD, required a drainage procedure in spite of repeated pyloric dilatation. During the mean follow-up period of 26 months (range: 10-46), the only symptom was moderate diarrhea in 4 patients, which became well with medical treatment or spontaneously.
Videoendoscopic truncal vagotomy seems to be an alternative treatment regimen for the management of chronic duodenal ulcer in a group of selected patients, as a simple, surgeon independent and efficient procedure. Instead of routine addition of a drainage procedure after truncal vagotomy, which may improve the morbidity, observation of the patient after truncal vagotomy with dietary caution supplementary to prokinetic medication may be the chosen method in some patients.
背景/目的:本文描述了一项针对一系列选定的慢性非梗阻性难治性十二指肠溃疡患者,进行的前瞻性试验中,不进行引流手术的视频内镜双侧迷走神经切断术的手术技术和初步结果。
伊斯坦布尔医学院医院外科成功地为32例慢性十二指肠溃疡患者实施了视频腹腔镜和视频胸腔镜下迷走神经切断术。这些接受双侧迷走神经切断术(BTV)且不进行引流手术的患者,是根据无幽门梗阻和胃酸过多的选择性指征挑选出来的。作为一项前瞻性试验,仅对20例患者在迷走神经切断术的同一阶段进行了内镜下幽门球囊扩张术(PBD)。研究了胃酸分泌试验和内镜检查的结果。
所有患者在严格随访下对单纯迷走神经切断术耐受性良好,术后24小时开始给予半流质饮食和促动力药物。基础胃酸分泌量(BAO)和高峰胃酸分泌量(PAO)的分泌试验平均下降分别为70.6%和79.5%。术后2个月的内镜检查显示,能够进行随访的患者溃疡愈合。1例部分幽门狭窄患者接受了BTV和PBD手术,尽管反复进行幽门扩张,仍需要进行引流手术。在平均26个月(范围:10 - 46个月)的随访期内,唯一的症状是4例患者出现中度腹泻,经药物治疗或自行缓解。
视频内镜下迷走神经切断术似乎是一组选定患者中治疗慢性十二指肠溃疡的一种替代治疗方案,是一种简单、独立于外科医生且有效的手术。在迷走神经切断术后,可不常规增加引流手术(这可能会增加发病率),对于一些患者,在迷走神经切断术后谨慎观察患者,并辅以饮食调整和促动力药物,可能是更好的选择。