O'Brien J D, Lium J H, Parosa J F, Deyoung B R, Wick M R, Trulock E P
Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Am J Respir Crit Care Med. 1995 Jun;151(6):2033-6. doi: 10.1164/ajrccm.151.6.7767554.
The evolution of lung transplantation has offered an additional treatment option for patients with a variety of end-stage lung diseases, including some with systemic disorders. Lymphangiomyomatosis (LAM) is a multisystem disease of premenopausal women. The lung is the most frequently involved vital organ, and respiratory failure is the most common case of death. A small number of patients with LAM have undergone lung transplantation. This report describes a case of recurrent LAM in the allograft after single lung transplantation and discusses the implications of this finding.
肺移植的发展为患有各种终末期肺部疾病(包括一些患有全身性疾病的患者)提供了额外的治疗选择。淋巴管平滑肌瘤病(LAM)是一种绝经前女性的多系统疾病。肺是最常受累的重要器官,呼吸衰竭是最常见的死亡原因。少数LAM患者接受了肺移植。本报告描述了一例单肺移植后同种异体移植物中LAM复发的病例,并讨论了这一发现的意义。