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Gene therapy for HIV infection.

作者信息

Lever A M

机构信息

University of Cambridge, Department of Medicine, Addenbrooke's Hospital, UK.

出版信息

Br Med Bull. 1995 Jan;51(1):149-66. doi: 10.1093/oxfordjournals.bmb.a072944.

DOI:10.1093/oxfordjournals.bmb.a072944
PMID:7767641
Abstract

The genetic approach to HIV infection is still very young and a number of different stages in the viral life cycle are being studied as targets for gene therapy, using a wide variety of modalities for gene delivery. Several gene therapy protocols for AIDS have been approved and when this article is published these may be in progress. In this chapter the scientific background to these in vivo studies is reviewed.

摘要

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Systemic T cell-independent tumor immunity after transplantation of universal receptor-modified bone marrow into SCID mice.将通用受体修饰的骨髓移植到SCID小鼠体内后的全身性非T细胞依赖性肿瘤免疫。
J Exp Med. 1996 Dec 1;184(6):2261-9. doi: 10.1084/jem.184.6.2261.