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[不同系列活麻疹疫苗接种动物器官中特异性抗原的定位]

[Localization of specific antigen in the organs of animals inoculated with different series of live measles vaccine].

作者信息

Gorshunova L P, Maksimova-Todorova V A, Romanov V A, Vanag K A, Nabokova A V

出版信息

Biull Eksp Biol Med. 1978 May;85(5):567-9.

PMID:77691
Abstract

Specific antigen was identified by the immunofluorescent test in the walls of the brain blood vessels, in the neurons, and in the glial cells of albino newborn mice and Syrian hamsters inoculated subcutaneously with 4 different batches of live measles vaccine. The pathomorphological test of the brain tissue revealed mainly vascular disturbances. The data obtained testify to the presence of residual neurotropism in the attenuated measles virus (strain "L-16").

摘要

通过免疫荧光试验在经皮下接种4批不同活麻疹疫苗的白化新生小鼠和叙利亚仓鼠的脑血壁、神经元和神经胶质细胞中鉴定出特异性抗原。脑组织的病理形态学检查主要显示血管紊乱。所获数据证明减毒麻疹病毒(“L-16”株)存在残余嗜神经性。

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