[解离的γ球蛋白的变应原性降低]
[Decreased anaphylactogenic properties of disaggregated gamma-globulin].
作者信息
Sofronov B N, Shemerovskaia T G
出版信息
Biull Eksp Biol Med. 1978 May;85(5):575-7.
PMID:77692
Abstract
Immunological properties of native, aggregated, and disaggregated (tolerogenic) human gamma-globulin were compared in experiments on mice and guinea pigs. Disaggregated preparation was shown to give diminished local and general hypersensitivity reaction in sensitized animals and had decreased ability to induce secondary humoral immune response.
摘要
在对小鼠和豚鼠进行的实验中，比较了天然、聚集和分解（致耐受性）人γ球蛋白的免疫学特性。结果显示，分解制剂在致敏动物中引起的局部和全身过敏反应减弱，且诱导二次体液免疫反应的能力降低。
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