大肠杆菌K-12和鼠伤寒沙门氏菌LT2中R1特异性染色体转移的比较研究。
Comparative study of R1-specific chromosomal transfer in Escherichia coli K-12 and salmonella typhimurium LT2.
作者信息
Hedén L O, Meynell E
出版信息
J Bacteriol. 1976 Jul;127(1):51-8. doi: 10.1128/jb.127.1.51-58.1976.
Abstract
High-frequency transfer of the chromosomal trp region by R1 observed in Escherichia coli (Pearce and Meynell, 1968) also occurs in Salmonella typhimurium. The reaction is recA independent in both species. The origin of transfer lies within a segment of the chromosome that is inverted in S. typhimurium relative to E. coli, and thus transfer occurs in a different direction in the two species. The character of R1 that is responsible, known as Tfa+, may be lost without affecting other properties of the R factor such as its own transfer.
摘要
在大肠杆菌中观察到的由R1介导的染色体色氨酸区域的高频转移（Pearce和Meynell，1968）在鼠伤寒沙门氏菌中也会发生。在这两个物种中，该反应均不依赖recA。转移起始于染色体的一个片段内，该片段在鼠伤寒沙门氏菌中相对于大肠杆菌是倒置的，因此在这两个物种中转移方向不同。负责此功能的R1特性称为Tfa +，即使丧失也不会影响R因子的其他特性，例如其自身的转移能力。
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