大肠杆菌C中R因子介导的极化染色体转移
R factor-mediated polarized chromosomal transfer in Escherichia coli C.
作者信息
Hedén L O, Rutberg L
出版信息
J Bacteriol. 1976 Jul;127(1):46-50. doi: 10.1128/jb.127.1.46-50.1976.
Abstract
Five transferable drug resistance factors (R factors) with the ability to bring about chromosomal transfer in Escherichia coli C were investigated with respect to the direction and origin of chromosome transfer. They were found to constitute two groups, both with a clockwise direction of transfer. One group has its origin of transfer between arg and pro, and the other group has its origin of transfer between try and man on the E. coli C chromosome. With one R factor in particular, the rapid increase in the production of recombinants was followed by a decrease in numbers as mating was prolonged.
摘要
研究了五个具有在大肠杆菌C中实现染色体转移能力的可转移耐药因子（R因子）的染色体转移方向和起源。发现它们构成两组，两组的转移方向均为顺时针。一组的转移起点在arg和pro之间，另一组的转移起点在大肠杆菌C染色体的try和man之间。特别是对于一个R因子，随着交配时间延长，重组体产量迅速增加之后数量会减少。
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