Rowley J D
Department of Medicine, University of Chicago Medical Center, IL 60637-1470, USA.
J Nucl Med. 1995 Jun;36(6 Suppl):22S-24S.
Many chromosomal aberrations in neoplastic tumor cells are specific for tumor types. These aberrations include both gains and losses of chromosomes (or chromosome regions) as well as translocations. The use of molecular probes to identify these aberrations may have potential application in the design of various cancer therapies that target the aberrant genes.
