Robertson D D, Ireland D J
Department of Otolaryngology, University of Manitoba Faculty of Medicine and Health Sciences Centre, Winnipeg.
J Otolaryngol. 1995 Feb;24(1):3-8.
A pilot study was undertaken in our Vestibular Disorders Clinic to re-evaluate the clinical benefits of vestibular evoked myogenic potentials (VEMP). In seven normal subjects and 20 documented unilateral peripheral vestibular disorder patients, electromyograms were recorded from surface electrodes over the sternomastoid muscles and averaged in response to 0.1-millisecond clicks played through headphones. Control patients demonstrated EMG positive-negative potentials (p14-n21) of equivalent latencies and amplitudes both ipsilateral and contralateral to the stimuli. In patients with documented unilateral peripheral vestibular disorders, the p14-n21 potentials were preserved in the presence of sensorineural hearing loss and absent in those patients with partial or total vestibular loss. A high directional correlation is noted between the p14-n21 potential and gold-standard caloric testing. We suspect the origin of the response may be in the saccule and suggest that VEMP testing may be useful in assessing intact vestibulocollic pathways in humans.
我们的前庭疾病诊所开展了一项初步研究，以重新评估前庭诱发肌源性电位（VEMP）的临床益处。在7名正常受试者和20名已确诊的单侧周围性前庭疾病患者中，通过表面电极记录胸锁乳突肌的肌电图，并对通过耳机播放的0.1毫秒咔嗒声做出的反应进行平均。对照患者在刺激同侧和对侧均表现出潜伏期和振幅相当的肌电图正负电位（p14-n21）。在已确诊的单侧周围性前庭疾病患者中，p14-n21电位在存在感音神经性听力损失的情况下得以保留，而在部分或完全前庭丧失的患者中则不存在。p14-n21电位与金标准冷热试验之间存在高度的方向相关性。我们怀疑该反应的起源可能在内耳球囊，并表明VEMP测试可能有助于评估人类完整的前庭-颈反射通路。
