Goldiner P L, Carlon G C, Cvitkovic E, Schweizer O, Howland W S
Br Med J. 1978 Jun 24;1(6128):1664-7. doi: 10.1136/bmj.1.6128.1664.
Patients treated with bleomycin are at risk of developing the acute adult respiratory distress syndrome post-operatively. In a prospective study of 12 patients who had received bleomycin preoperatively and were undergoing removal of retroperitoneal lymph nodes or pulmonary metastases several preventive factors were established. These were the use of low concentrations of inspired oxygen during operation and in the immediate postoperative period, careful monitoring of fluid replacement, and restriction of crystalloids in favour of colloids.
接受博来霉素治疗的患者术后有发生急性成人呼吸窘迫综合征的风险。在一项对12例术前接受过博来霉素治疗且正在接受腹膜后淋巴结清除术或肺转移灶清除术的患者的前瞻性研究中,确定了几个预防因素。这些因素包括在手术期间和术后即刻使用低浓度的吸入氧、仔细监测液体补充情况以及限制晶体液而支持胶体液。