Buckmaster M J, Hyde G L, Arden W A, Nypaver T J, Endean E D, Schwarcz T H, Kuo C S
Department of Surgery, University of Kentucky Chandler Medical Center, Lexington 40536-0084, USA.
J Vasc Surg. 1995 May;21(5):818-21; discussion 821-2. doi: 10.1016/s0741-5214(05)80013-8.
The purpose of this study was to develop an angioscopic technique to visualize the endoluminal surface of the aorta and to guide vascular stent placement.
A fiberoptic angioscope, fitted with a balloon at its tip, was passed via a carotid arteriotomy into the abdominal aorta of seven anesthetized pigs. Saline solution inflation of the balloon allowed for blood displacement and clear visualization of the endoluminal anatomy. After the left renal artery orifice had been identified with angioscopy, a catheter was inserted via a left femoral sheath to cannulate the orifice under direct visualization. The position of the catheter was verified angiographically. A vascular stent was loaded onto an angioplasty balloon, inserted through a right femoral arteriotomy, positioned by use of angioscopic visualization, and deployed immediately below the left renal artery orifice.
The aortic trifurcation and the lumbar and renal artery orifices were clearly visualized in every animal. Vascular stents were placed in seven animals within an average of 3.14 +/- 1.14 mm (mean +/- SEM, range 0 to 8 mm) below the inferior rim of the left renal artery orifice. No stents were positioned above a renal artery orifice or obstructed blood flow.
This angioscopic technique permitted detailed evaluation of aortic endoluminal anatomy and precise implantation of vascular stents. Direct endovascular visualization may facilitate other endovascular procedures, including endovascular grafting.
本研究的目的是开发一种血管内镜技术,以可视化主动脉腔内表面并指导血管支架置入。
将顶端装有球囊的纤维光学血管内镜经颈动脉切开术插入7只麻醉猪的腹主动脉。通过向球囊内注入生理盐水来置换血液,从而清晰地观察腔内解剖结构。在通过血管内镜识别出左肾动脉开口后,经左股鞘插入导管,在直视下将导管插入该开口。通过血管造影术验证导管的位置。将血管支架装载到血管成形球囊上,并通过右股动脉切开术插入,利用血管内镜可视化进行定位,然后立即在左肾动脉开口下方展开。
每只动物的主动脉三叉分支以及腰动脉和肾动脉开口均清晰可见。在7只动物中,血管支架放置在左肾动脉开口下缘下方平均3.14 +/- 1.14毫米(平均值 +/- 标准误,范围0至8毫米)处。没有支架放置在肾动脉开口上方或阻碍血流。
这种血管内镜技术允许对主动脉腔内解剖结构进行详细评估,并精确植入血管支架。直接的血管内可视化可能有助于其他血管内手术,包括血管内移植术。