生长抑素受体3信使核糖核酸在大鼠脊髓运动神经元及脊髓神经节感觉神经元中的表达。
Expression of somatostatin receptor 3 mRNA in the motorneurones of the rat spinal cord, and the sensory neurones of the spinal ganglia.
作者信息
Señaris R M, Schindler M, Humphrey P P, Emson P C
机构信息
Department of Neurobiology, Babraham Institute, Cambridge, UK.
出版信息
Brain Res Mol Brain Res. 1995 Mar;29(1):185-90. doi: 10.1016/0169-328x(94)00275-j.
At least five different types of somatostatin receptors (SSTRs): SSTR1-5 have been recently cloned. Here, we report the distribution of somatostatin receptor 3 (SSTR3) mRNA in spinal cord and spinal ganglia by in situ hybridization. We demonstrate the presence of this transcript in motorneurones of the spinal cord and other motor nuclei of the brain stem, and in the sensory neurones of the spinal ganglia. These data suggest a role for SSTR3 in motor and sensory functions.
最近已克隆出至少五种不同类型的生长抑素受体（SSTRs）：SSTR1 - 5。在此，我们通过原位杂交报告生长抑素受体3（SSTR3）mRNA在脊髓和脊神经节中的分布。我们证明该转录本存在于脊髓的运动神经元、脑干的其他运动核以及脊神经节的感觉神经元中。这些数据表明SSTR3在运动和感觉功能中发挥作用。
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