Kaplan J M, Roitman M F, Grill H J
Department of Psychology, University of Pennsylvania, Philadelphia 19104, USA.
Neurosci Biobehav Rev. 1995 Spring;19(1):89-98. doi: 10.1016/0149-7634(94)00023-t.
In ingestive taste reactivity analysis, the rhythmic oral motor responses observed during intraoral infusion of fluids normally ingested by rats are categorized and counted. These rhythmic movements can be likened to spout-licking in several respects. Both are emitted in the same frequency range (5-8 Hz), organized in a burst/pause pattern, and serve the function of intraoral transport of fluid into position for swallowing. The parallel suggests that a temporal pattern analysis, based on the spout-licking literature, can be fruitfully applied to the rhythmic movements that attend intraoral infusion. We provide a demonstration of such an analysis using an electromyographic (EMG) recording-based method for automated event detection. Eight rats received a 37.5% glucose solution (1.0 ml/min) in a series of 120 s infusion trials (45 s intertrial intervals) that was extended until the fluid was rejected. Movement counts declined 19.1% from the first to the last complete trial. Parameters derived from the pattern analysis (number of bursts, mean burst duration, pause durations, coefficient of variation for the distribution of within-burst intermovement intervals) were affected to a greater extent. The results indicate the potential value of temporal pattern analysis for various applications of the taste reactivity paradigm.
在摄取性味觉反应分析中，对大鼠口腔内注入其正常摄入的液体时所观察到的节律性口腔运动反应进行分类和计数。这些节律性运动在几个方面可与喷嘴舔舐相类比。两者都在相同的频率范围（5 - 8赫兹）内发出，以突发/暂停模式组织，并起到将口腔内液体输送到吞咽位置的作用。这种相似性表明，基于喷嘴舔舐文献的时间模式分析可以有效地应用于口腔内注入时伴随的节律性运动。我们使用基于肌电图（EMG）记录的自动事件检测方法对此类分析进行了演示。八只大鼠在一系列120秒的输注试验（试验间隔45秒）中接受37.5%的葡萄糖溶液（1.0毫升/分钟），试验持续进行直至液体被拒斥。从第一次完整试验到最后一次完整试验，运动计数下降了19.1%。从模式分析得出的参数（突发次数、平均突发持续时间、暂停持续时间、突发内运动间隔分布的变异系数）受到的影响更大。结果表明时间模式分析在味觉反应范式的各种应用中的潜在价值。
