Gearhart J P, Ben-Chaim J, Jeffs R D, Sanders R C
Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins Hospital, Baltimore, Maryland, USA.
Obstet Gynecol. 1995 Jun;85(6):961-4. doi: 10.1016/0029-7844(95)00069-4.
To define ultrasonographic criteria for the prenatal diagnosis of classic bladder exstrophy.
Forty-three prenatal ultrasound scans were studied from 25 pregnancies in which live delivery of an infant with classic bladder exstrophy occurred. The diagnosis of bladder exstrophy could be made retrospectively in 29 prenatal studies from 17 pregnancies. The time of the fetal ultrasound varied from 14-36 weeks' gestation (mean 23). The diagnosis of bladder exstrophy was made before delivery in only three cases.
Five factors associated with bladder exstrophy were identified: 1) The bladder was not visualized on ultrasound in 12 of 17 cases (71%); 2) a lower abdominal bulge representing the exstrophied bladder was seen in eight of 17 cases (47%); 3) a small penis with anteriorly displaced scrotum was identified in eight of 14 males (57%); 4) the umbilical insertion was low set in five of 17 cases (29%); and 5) abnormal widening of the iliac crests was seen in three of 17 cases (18%).
The prenatal diagnosis of bladder exstrophy should be considered any time the bladder is not visualized or any of the aforementioned factors are noted.
确定经典型膀胱外翻产前诊断的超声标准。
对25例分娩出经典型膀胱外翻婴儿的妊娠进行了43次产前超声检查。在17例妊娠的29次产前检查中可回顾性做出膀胱外翻的诊断。胎儿超声检查时间为妊娠14 - 36周(平均23周)。仅3例在分娩前做出膀胱外翻的诊断。
确定了与膀胱外翻相关的五个因素:1)17例中的12例(71%)超声未显示膀胱;2)17例中的8例(47%)可见代表外翻膀胱的下腹部膨隆;3)14例男性中的8例(57%)发现阴茎小且阴囊前移;4)17例中的5例(29%)脐部附着位置低;5)17例中的3例(18%)可见髂嵴异常增宽。
每当超声未显示膀胱或发现任何上述因素时,均应考虑经典型膀胱外翻的产前诊断。