Hollowood K, Fletcher C D
Department of Histopathology, St Thomas's Hospital, London, England, U.K.
Semin Diagn Pathol. 1995 Feb;12(1):87-97.
Although it is well known that a variety of benign mesenchymal neoplasms and reactive proliferations may mimic sarcomas, the fact that some types of sarcoma commonly are misinterpreted as benign is less widely appreciated. This review considers five such lesions in soft tissue: low grade fibromyxoid sarcoma, low grade myxofibrosarcoma (myxoid "MFH"), well differentiated liposarcoma (atypical lipoma), epithelioid sarcoma, and so-called inflammatory fibrosarcoma. Principal reasons for their underrecognition are their generally bland cytology, often relative hypocellularity, and indolent clinical course. Common to several of these lesions, however, is a tendency for histological and hence biological progression in local recurrences, underlining the importance of accurate diagnosis and adequate treatment of the primary lesion. This review considers the principal clinicopathologic features, differential diagnosis and (where appropriate) nosologic status of this treacherous group of neoplasms.
尽管众所周知，多种良性间叶性肿瘤和反应性增生可能会模仿肉瘤，但某些类型的肉瘤通常被误诊为良性这一事实却鲜为人知。本综述探讨软组织中的五种此类病变：低级别纤维黏液样肉瘤、低级别黏液纤维肉瘤（黏液样“恶性纤维组织细胞瘤”）、高分化脂肪肉瘤（非典型脂肪瘤）、上皮样肉瘤以及所谓的炎性纤维肉瘤。它们未被充分认识的主要原因是其细胞学表现通常平淡、细胞数量往往相对较少以及临床过程惰性。然而，这些病变中有几种的共同特点是，局部复发时有组织学进而生物学进展的趋势，这凸显了准确诊断和充分治疗原发病变的重要性。本综述探讨了这一组具有潜在风险的肿瘤的主要临床病理特征、鉴别诊断以及（如适用）分类地位。
