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[症状性胰腺分裂症的外科治疗]

[Surgical treatment of symptomatic pancreas divisum].

作者信息

Søndenaa K, Søreide O, Nesje L B, Andersen E, Nesvik I, Søreide J A

机构信息

Kirurgisk avdeling, Haukeland Sykehus, Bergen.

出版信息

Tidsskr Nor Laegeforen. 1995 Apr 30;115(11):1365-7.

PMID:7770833
Abstract

Pancreas divisum is found in 5% of the population. It is linked to three clinical entities; recurrent epigastric pain, and acute and chronic pancreatitis. The relation between chronic pancreatitis and pancreas divisum is, however, uncertain. Pancreas divisum is controversial as a cause of acute pancreatitis and abdominal pain. However, this association probably exists as surgical sphincteroplasty of the minor papilla alleviate symptoms in a high proportion of patients. We have treated two patients surgically. Patient 1 was hospitalized 11 times because of recurrent acute pancreatitis. Two and a half years after sphincteroplasty he has had no further attacks of abdominal pain. Patient 2 had had recurrent epigastric pain, mostly related to meals, since early childhood. Secretin stimulation initially showed normal pancreatic duct dilatation and emptying. After sphincteroplasty, and reoperation for stricture, she can eat normally without pain one year after the last operation. We conclude that in selected patients surgical treatment of symptomatic pancreas divisum is beneficial. Sphincteroplasty should be considered as treatment in patients with pancreas divisum and recurrent acute pancreatitis or pain, as long as other causes are excluded.

摘要

胰腺分裂在5%的人群中被发现。它与三种临床情况有关;复发性上腹部疼痛、急性和慢性胰腺炎。然而,慢性胰腺炎与胰腺分裂之间的关系尚不确定。胰腺分裂作为急性胰腺炎和腹痛的病因存在争议。然而,这种关联可能存在,因为对小乳头进行手术括约肌成形术可使很大一部分患者的症状得到缓解。我们对两名患者进行了手术治疗。患者1因复发性急性胰腺炎住院11次。括约肌成形术后两年半,他没有再出现腹痛发作。患者2自幼年起就有复发性上腹部疼痛,大多与进餐有关。促胰液素刺激试验最初显示胰管扩张和排空正常。在进行括约肌成形术以及因狭窄进行再次手术后,她在最后一次手术后一年能够正常饮食且无疼痛。我们得出结论,对于有症状的胰腺分裂患者,手术治疗是有益的。对于胰腺分裂且有复发性急性胰腺炎或疼痛的患者,只要排除了其他病因,就应考虑将括约肌成形术作为治疗方法。

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