Maksomovskaia L N, Tsarev V N, Davydova M M, Shishchenko V M
Stomatologiia (Mosk). 1995;74(1):16-9.
Clinical and laboratory examinations of 86 patients with relapsing aphthous stomatitis making use of a complex of clinical, immunological, cytochemical, and microbiological methods, helped specify the clinico-anamnestic features in the course of this disease. An immunobacterial concept of the pathogenesis of relapsing aphthous stomatitis has been formulated; according to this concept, the disease is initiated by disorders of T and B immunity system and nonspecific defense factors, leading to increase of the content and virulence of oral microflora, and thus stimulating the bacterial sensitization of the organism of patients with relapsing aphthous stomatitis.
采用临床、免疫、细胞化学和微生物学等综合方法，对86例复发性阿弗他口炎患者进行临床和实验室检查，有助于明确该病病程中的临床记忆特征。已形成复发性阿弗他口炎发病机制的免疫细菌学概念；根据这一概念，该病由T和B免疫系统及非特异性防御因子紊乱引发，导致口腔微生物群落数量增加和毒力增强，从而刺激复发性阿弗他口炎患者机体的细菌致敏。
