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目前、曾经以及从未参加过美沙酮治疗的注射吸毒者中的艾滋病毒风险行为。

HIV risk-taking behaviour among injecting drug users currently, previously and never enrolled in methadone treatment.

作者信息

Baker A, Kochan N, Dixon J, Wodak A, Heather N

机构信息

National Drug & Alcohol Research Centre, University of New South Wales, Sydney, Australia.

出版信息

Addiction. 1995 Apr;90(4):545-54. doi: 10.1046/j.1360-0443.1995.9045458.x.

Abstract

This study compares the injecting and sexual risk-taking behaviour among injecting drug users (IDUs) currently, previously and never enrolled in methadone maintenance treatment (MMT). All subjects had injected during the 6 months prior to the day of interview. The current MMT group showed significantly lower injecting risk-taking behaviour subscale scores on the HIV Risk-taking Behaviour Scale (HRBS) of the Opiate Treatment Index than the previous MMT and non-MMT groups together. The current MMT group differed from the other two groups in the frequency of injecting and cleaning of injection equipment with bleach. There was no difference between the current MMT group and the other two groups combined in sexual risk-taking behaviour scores on the HRBS. There were no differences between the previous MMT and non-MMT groups in injecting and sexual risk-taking behaviour. HIV seroprevalence was low and there was no difference in seroprevalence between groups. Thus, IDUs currently enrolled in MMT are at reduced risk for HIV infection when compared with IDUs who have previously or never been enrolled in MMT. However, the absence of a difference between the current MMT and other two groups in frequency of sharing behaviours suggests the need for additional strategies among MMT clients to reduce needle-sharing. Possible strategies include the application of relapse prevention interventions and the availability of sterile injecting equipment in MMT clinics. Further research is needed to identify factors which increase attraction and retention of IDUs to MMT.

摘要

本研究比较了目前正在接受美沙酮维持治疗(MMT)、曾经接受过MMT以及从未接受过MMT的注射吸毒者(IDU)的注射行为和性冒险行为。所有受试者在访谈日前6个月内均有注射行为。在阿片类药物治疗指数的HIV冒险行为量表(HRBS)上,目前接受MMT治疗的组在注射冒险行为分量表得分上显著低于曾经接受MMT治疗的组和未接受MMT治疗的组之和。目前接受MMT治疗的组在注射频率和使用漂白剂清洁注射设备方面与其他两组不同。目前接受MMT治疗的组与其他两组在HRBS上的性冒险行为得分方面没有差异。曾经接受MMT治疗的组和未接受MMT治疗的组在注射行为和性冒险行为方面没有差异。HIV血清阳性率较低,各群组之间的血清阳性率没有差异。因此,与曾经或从未接受过MMT治疗的IDU相比,目前接受MMT治疗的IDU感染HIV的风险较低。然而,目前接受MMT治疗的组与其他两组在共用行为频率上没有差异,这表明需要在接受MMT治疗的患者中采取额外策略以减少针头共用。可能的策略包括应用预防复发干预措施以及在MMT诊所提供无菌注射设备。需要进一步研究以确定增加IDU对MMT治疗的吸引力和留存率的因素。

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