Neims D M, McNeill J, Giles T R, Todd F
Focus Associates, Behavioral Health Resources, Lacey, Washington 98503-5719, USA.
Int J Eat Disord. 1995 Apr;17(3):211-28. doi: 10.1002/1098-108x(199504)17:3<211::aid-eat2260170302>3.0.co;2-i.
Estimates of the incidence of laxative abuse in bulimics and in the community-at-large vary widely for various population samples. This review identified 73 studies in which laxative abuse could be assessed in bulimics, nonbulimics, and the community-at-large. Relative risk values for laxative abuse among population subsamples were estimated by moment methods statistical procedure based on mixed model analysis. Results indicated that the lifetime occurrence for laxative abuse behavior in the community-at-large was 4.18%. Bulimic behavior increased the risk for laxative abuse 3.57-fold to 14.94%. Several methodologic and population parameter characteristics are examined for their select impact on laxative abuse. Review of medical nomenclature for classifying laxative substances, iatragenic effects of laxative abuse, and assessment recommendations are also included.
对于不同的人群样本,贪食症患者以及普通人群中泻药滥用的发生率估计差异很大。本综述确定了73项研究,在这些研究中可以评估贪食症患者、非贪食症患者以及普通人群中的泻药滥用情况。基于混合模型分析,通过矩法统计程序估计了人群亚样本中泻药滥用的相对风险值。结果表明,普通人群中泻药滥用行为的终生发生率为4.18%。贪食行为使泻药滥用风险增加3.57倍至14.94%。研究了几种方法学和人群参数特征对泻药滥用的特定影响。还包括对泻药物质分类的医学术语回顾、泻药滥用的医源性影响以及评估建议。