饮食失调个体中与滥用泻药相关的特征。
Features associated with laxative abuse in individuals with eating disorders.
作者信息
Tozzi Federica, Thornton Laura M, Mitchell James, Fichter Manfred M, Klump Kelly L, Lilenfeld Lisa R, Reba Lauren, Strober Michael, Kaye Walter H, Bulik Cynthia M
机构信息
Department of Psychiatry, University of North Carolina at Chapel Hill, 1st floor Neurosciences Hospital, CB #7160, Chapel Hill, North Carolina 27599-7160, USA.
出版信息
Psychosom Med. 2006 May-Jun;68(3):470-7. doi: 10.1097/01.psy.0000221359.35034.e7.
OBJECTIVE
Laxative abuse is common in patients with anorexia and bulimia nervosa and has been associated with longer duration of illness, suicide attempts, impulsivity, and greater eating and general psychopathology. We explored the extent to which laxative abuse was associated with specific psychopathological features across eating disorder subtypes.
METHODS
Participants were 1021 individuals from the multisite, International Price Foundation Genetic Studies. Axis I disorders, personality disorders and traits, and obsessive compulsive features were assessed.
RESULTS
Laxative abuse was associated with worse eating disorder and general psychopathology and higher prevalence of borderline personality disorder (BPD). Symptom level analyses revealed that specific features of BPD, including suicidality and self-harm, feelings of emptiness, and anger, were most strongly associated with laxative abuse.
CONCLUSIONS
The function of laxative abuse may differ across individuals with eating disorders, alternatively serving as a method of purging and a form of self-harm.
目的
泻药滥用在神经性厌食症和神经性贪食症患者中很常见，且与病程延长、自杀企图、冲动性以及更严重的饮食和一般精神病理学问题有关。我们探讨了泻药滥用与不同饮食障碍亚型的特定精神病理学特征之间的关联程度。
方法
参与者来自多中心的国际价格基金会基因研究，共1021人。评估了轴I障碍、人格障碍和特质以及强迫特征。
结果
泻药滥用与更严重的饮食障碍和一般精神病理学问题以及边缘性人格障碍（BPD）的更高患病率相关。症状水平分析表明，BPD的特定特征，包括自杀和自我伤害、空虚感和愤怒，与泻药滥用的关联最为密切。
结论
泻药滥用在患有饮食障碍的个体中的作用可能不同，它既可以作为一种清除方式，也可以作为一种自我伤害的形式。
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