Vatsis K P, Weber W W, Bell D A, Dupret J M, Evans D A, Grant D M, Hein D W, Lin H J, Meyer U A, Relling M V
Department of Pharmacology, Medical School, University of Michigan, Ann Arbor 48109-0632, USA.
Pharmacogenetics. 1995 Feb;5(1):1-17. doi: 10.1097/00008571-199502000-00001.
A consolidated classification system is described for prokaryotic and eukaryotic N-acetyltransferases in accordance with the international rules for gene nomenclature. The root symbol (NAT) specifically identifies the genes that code for the N-acetyltransferases, and NAT* loci encoding proteins with similar function are distinguished by Arabic numerals. Allele characters, denoted by Arabic numbers or by a combination of Arabic numbers and uppercase Latin letters, are separated from gene loci by an asterisk, and the entire gene-allele symbols are italicized. Alleles at the different NAT* loci have been numbered chronologically irrespective of the species of origin. For designation of genotypes at a single NAT* locus, a slash serves to separate the alleles; in phenotype designations, which are not italicized, alleles are separated by a comma.
根据国际基因命名规则，描述了一种针对原核生物和真核生物N - 乙酰基转移酶的综合分类系统。根符号（NAT）专门用于识别编码N - 乙酰基转移酶的基因，编码具有相似功能蛋白质的NAT基因座则用阿拉伯数字区分。等位基因特征由阿拉伯数字或阿拉伯数字与大写拉丁字母的组合表示，通过星号与基因座分隔开，整个基因 - 等位基因符号用斜体表示。不同NAT基因座的等位基因已按时间顺序编号，而不考虑其来源物种。对于单个NAT*基因座的基因型指定，用斜线分隔等位基因；在非斜体的表型指定中，等位基因用逗号分隔。
