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儿童卡他莫拉菌(布兰汉菌属)菌血症。两例病例报告及文献复习

Moraxella (Branhamella) catarrhalis bacteremia in children. A report of two patients and review of the literature.

作者信息

Meyer G A, Shope T R, Waecker N J, Lanningham F H

机构信息

Department of Pediatrics, Naval Medical Center, San Diego, California 92134-5000, USA.

出版信息

Clin Pediatr (Phila). 1995 Mar;34(3):146-50. doi: 10.1177/000992289503400305.

DOI:10.1177/000992289503400305
PMID:7774141
Abstract

We report two cases of Moraxella catarrhalis (M. catarrhalis) bacteremia in apparently healthy children. One patient had bilateral otitis media and the other had pharyngitis and sinusitis; both patients had uncomplicated clinical courses. A literature review revealed 22 reported cases of M. catarrhalis bacteremia in children, 14 (63%) of which occurred in patients who had no identified underlying condition. Eight (36%) cases were seen in children who were immunocompromised. Nine (40%) patients presented with either purpura, petechia, or a maculopapular rash. M. catarrhalis is well known as a respiratory pathogen, but it has not been recognized as a common cause of unsuspected bacteremia in children.

摘要

我们报告了两例表面健康儿童感染卡他莫拉菌(M. catarrhalis)败血症的病例。一名患者患有双侧中耳炎,另一名患者患有咽炎和鼻窦炎;两名患者的临床病程均无并发症。文献综述显示,有22例儿童卡他莫拉菌败血症的报告病例,其中14例(63%)发生在未发现潜在疾病的患者中。8例(36%)病例见于免疫功能低下的儿童。9例(40%)患者出现紫癜、瘀点或斑丘疹。卡他莫拉菌是一种众所周知的呼吸道病原体,但尚未被认为是儿童不明原因败血症的常见病因。

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BMC Infect Dis. 2016 Feb 9;16:73. doi: 10.1186/s12879-016-1408-3.
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Mucosal immunization with the Moraxella Catarrhalis porin m35 induces enhanced bacterial clearance from the lung: a possible role for opsonophagocytosis.黏膜免疫接种卡他莫拉菌孔蛋白 m35 可增强肺部细菌清除:调理吞噬作用的可能作用。
Front Immunol. 2011 May 16;2:13. doi: 10.3389/fimmu.2011.00013. eCollection 2011.
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Influence of Moraxella sp. colonization on the kidney proteome of farmed gilthead sea breams (Sparus aurata, L.).
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Moraxella catarrhalis M35 is a general porin that is important for growth under nutrient-limiting conditions and in the nasopharynges of mice.卡他莫拉菌M35是一种普通孔蛋白,对在营养限制条件下以及在小鼠鼻咽部的生长很重要。
J Bacteriol. 2008 Dec;190(24):7994-8002. doi: 10.1128/JB.01039-08. Epub 2008 Oct 17.
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