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[早产儿视网膜病变危险因素的研究]

[A study on risk factors of retinopathy of prematurity].

作者信息

Jiang Y R, Li X X, Qi H J

机构信息

Department of Ophthalmology, People's Hospital, Beijing Medical University.

出版信息

Zhonghua Yan Ke Za Zhi. 1994 Nov;30(6):427-30.

PMID:7774458
Abstract

Ocular fundi of 54 premature infants (age of gestation < 37 weeks) and 5 full-term babies with low body weight (< 2500 g) were examined at the forth week after birth. According to the international classification of retinopathy of prematurity, they were diagnosed as retinopathy of prematurity (ROP). The risk factors of the incidence of ROP were statistically analyzed, respectively. The results show that the lower the body weight, the shorter the gestation, the higher the oxygen concentration, the longer the oxygen administration, the higher the incidence of ROP. The incidences of ROP in the following baby groups, the body weight at birth < or = 1500 g, gestational weeks < or = 32 weeks, the oxygen concentration administered > 80%, and the duration of persistent oxygen administration > 5 days are significantly higher than those in the corresponding respective other groups. It is also demonstrated that the duration of the first time of oxygen administration and the complications of the newborn babies such as asphyxia, intracranial hemorrhage, anemia, pneumonia and blood transfusion have no effects on the incidence of ROP.

摘要

对54例早产儿(孕周<37周)和5例低体重足月儿(<2500g)在出生后第4周进行眼底检查。根据国际早产儿视网膜病变分类,将其诊断为早产儿视网膜病变(ROP)。分别对ROP发病的危险因素进行统计学分析。结果显示,体重越低、孕周越短、氧浓度越高、吸氧时间越长,ROP的发病率越高。出生体重≤1500g、孕周≤32周、吸氧浓度>80%、持续吸氧时间>5天的婴儿组ROP发病率明显高于相应的其他组。还表明首次吸氧时间及新生儿窒息、颅内出血、贫血、肺炎、输血等并发症对ROP发病率无影响。

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