Chen Y, Li X
People Eye Center, People's Hospital of Peking University, No 11 Beijing Xizhimen Nan Street, Beijing, 100044, China.
Br J Ophthalmol. 2006 Mar;90(3):268-71. doi: 10.1136/bjo.2005.078063.
To describe the characteristics of babies treated for severe retinopathy of prematurity (ROP) in a tertiary referral unit in China, to provide information to assist in determining screening criteria.
Information on consecutive babies referred to one eye department for treatment of stage 3 (prethreshold and threshold disease), and stages 4 and 5 ROP between January 2001 and May 2005 were retrieved from medical records.
Data from 114 babies were analysed. The number of babies treated increased from nine in 2001 to 52 in 2004. The numbers of infants in each stage of ROP were as follows: stage 3, 40 babies; stage 4, 19 babies, and stage 5, 55 cases. The mean gestational age (GA) was 29.8 (SD 1.9) weeks (range 26-34 weeks) and the mean birth weight (BW) was 1432 (319) g (range 760-2500 g). 31 babies had BWs more than 1500 g (27.2%). 10 cases (8.8%) had GAs more than 32 weeks, and 82 (71.9%) had GAs more than 28 weeks. Overall, 18 (16.2%) infants exceeded UK screening criteria, and 34 (30.4%) exceeded the criteria used in the United States. The median age at presentation was 5.5 months (range 1-72 months).
Comprehensive screening programmes for ROP are urgently needed in China. Screening criteria recommended by the American Academy of Pediatric Ophthalmology and Strabismus and the Royal College of Ophthalmologists, United Kingdom, may not be suitable for China where bigger, more mature babies are developing severe disease.
描述在中国一家三级转诊单位接受重度早产儿视网膜病变（ROP）治疗的婴儿的特征，为确定筛查标准提供信息。
从病历中检索2001年1月至2005年5月期间连续转诊至某眼科治疗3期（阈值前期和阈值期疾病）以及4期和5期ROP的婴儿信息。
分析了114名婴儿的数据。接受治疗的婴儿数量从2001年的9名增加到2004年的52名。ROP各阶段的婴儿数量如下：3期，40名婴儿；4期，19名婴儿；5期，55例。平均胎龄（GA）为29.8（标准差1.9）周（范围26 - 34周），平均出生体重（BW）为1432（319）克（范围760 - 2500克）。31名婴儿出生体重超过1500克（27.2%）。10例（8.8%）胎龄超过32周，82例（71.9%）胎龄超过28周。总体而言，18名（16.2%）婴儿超过了英国的筛查标准，34名（30.4%）超过了美国使用的标准。就诊时的中位年龄为5.5个月（范围1 - 72个月）。
中国迫切需要全面的ROP筛查项目。美国小儿眼科与斜视学会以及英国皇家眼科医师学院推荐的筛查标准可能不适用于中国，在中国，体型较大、更成熟的婴儿也会患严重疾病。
