Nieminen A, Sirén E, Wolf J, Asikainen S
Department of Periodontology, University of Helsinki, Finland.
J Clin Periodontol. 1995 Feb;22(2):153-61. doi: 10.1111/j.1600-051x.1995.tb00127.x.
The aim of the study was to find out which clinical, radiographic and microbiological variables can be used as prognostic criteria for the efficiency of the commonly used initial treatment protocol comprising scaling, root planning and instruction on oral hygiene in advanced adult periodontitis. 46 patients (mean age 48 years) with untreated, advanced periodontitis volunteered for the study. The clinical examination included recordings of plaque, gingival and calculus indices, probing pocket depths, bleeding and suppuration after probing, probing attachment levels and furcation involvements. Infrabony and furcation lesions were assessed from panoramic radiographs. Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis were cultured from the deepest, most inflamed periodontal Pockets, from surface of the tongue and from saliva. 3 months after the completion of non-surgical treatment comprising meticulous scaling and root planing and instruction on oral hygiene, the healing was assessed clinically, and 13 patients were assigned to a maintenance care programme (MC) and 33 to further treatment procedures (FT). Evaluation of the baseline clinical and radiographic data showed a significantly higher %s of > or = 6 mm deep periodontal pockets, surfaces with suppuration, and sites with subgingival calculus, as well as higher numbers of infrabony lesions, in FT-patients than in MC-patients. Subgingival A. actinomycetemcomitans was isolated at baseline in 55% of the FT-patients and in 38% of the MC-patients, and P. gingivalis in 27% and 23%, respectively. A. actinomycetemcomitans was eradicated by non-surgical treatment from only one patient. P. gingivalis was detected in 15% of the patients in both groups after treatment.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究的目的是找出哪些临床、影像学和微生物学变量可作为常用初始治疗方案疗效的预后标准,该方案包括在重度成人牙周炎患者中进行龈上洁治、根面平整及口腔卫生指导。46例未经治疗的重度牙周炎患者(平均年龄48岁)自愿参与本研究。临床检查包括记录菌斑、牙龈和牙石指数、探诊牙周袋深度、探诊后出血及化脓情况、探诊附着水平和根分叉病变。从全景X线片评估骨下袋和根分叉病变。从最深、炎症最严重的牙周袋、舌面和唾液中培养伴放线放线杆菌和牙龈卟啉单胞菌。在完成包括细致龈上洁治、根面平整及口腔卫生指导的非手术治疗3个月后,进行临床愈合评估,13例患者被分配至维护护理计划(MC)组,33例患者被分配至进一步治疗程序(FT)组。对基线临床和影像学数据的评估显示,FT组患者中牙周袋深度≥6mm、有化脓表面和龈下牙石部位的百分比显著更高,骨下袋病变数量也更多。基线时,55%的FT组患者和38%的MC组患者龈下分离出伴放线放线杆菌,牙龈卟啉单胞菌的分离率分别为27%和23%。非手术治疗仅使1例患者的伴放线放线杆菌被根除。治疗后两组均有15%的患者检测到牙龈卟啉单胞菌。(摘要截选至250词)