Sakai K, Nakagawa M, Fujita Y, Ishizuka N, Nakamura K, Hosoda S, Hashimoto A, Koyanagi H
Kichijoji Sakakibara Clinic, Tokyo.
J Cardiol. 1995 May;25(5):233-42.
This study investigated the changes in treatment procedures for mitral stenosis (MS) and mitral regurgitation (MR) against the background of a decrease in the incidence of rheumatic valvular disease. The study included 3,955 patients with MS undergoing closed mitral commissurotomy (CMC), open mitral commissurotomy (OMC), mitral valve replacement (MVR), or percutaneous transvenous mitral commissurotomy (PTMC) between 1952 and 1991, and 478 patients with MR undergoing MVR or mitral valvuloplasty in the Heart Institute of Japan, Tokyo Women's Medical College. The number of patients with MS undergoing surgical or catheter interventions has decreased and is now about 80 per year, a half of that experienced in the 1960s. CMC and OMC have been replaced by PTMC since the 1990s. The most popular treatment procedure is now MVR. The number of patients with MR undergoing surgery has increased to about 30 per year. Eighty percent of operations for MR are MVR and the others are mitral valvoplasty. Survey of the etiology of MR shows decreased rheumatic disease and increased degenerative disease. The incidence of MR due to ischemic heart disease and hypertrophic obstructive cardiomyopathy has slightly increased.
本研究调查了在风湿性瓣膜病发病率下降的背景下二尖瓣狭窄(MS)和二尖瓣反流(MR)治疗方法的变化。该研究纳入了1952年至1991年间在东京女子医科大学日本心脏研究所接受闭式二尖瓣交界切开术(CMC)、直视二尖瓣交界切开术(OMC)、二尖瓣置换术(MVR)或经皮经静脉二尖瓣交界切开术(PTMC)的3955例MS患者,以及478例接受MVR或二尖瓣成形术的MR患者。接受手术或导管介入治疗的MS患者数量有所减少,目前每年约80例,仅为20世纪60年代的一半。自20世纪90年代以来,CMC和OMC已被PTMC所取代。目前最常用的治疗方法是MVR。接受手术治疗的MR患者数量已增至每年约30例。80%的MR手术为MVR,其余为二尖瓣成形术。对MR病因的调查显示,风湿性疾病减少,退行性疾病增加。缺血性心脏病和肥厚性梗阻性心肌病所致MR的发病率略有上升。