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Human recombinant DNase in cystic fibrosis.

作者信息

Thomson A H

机构信息

Department of Paediatrics, John Radcliffe Hospital, Headington, Oxford.

出版信息

J R Soc Med. 1995;88 Suppl 25(Suppl 25):24-9.

PMID:7776324
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1295055/
Abstract
摘要

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Human recombinant DNase in cystic fibrosis.囊性纤维化中的人重组脱氧核糖核酸酶
J R Soc Med. 1995;88 Suppl 25(Suppl 25):24-9.
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New treatment for cystic fibrosis.
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Comment: cost of rhDNase in cystic fibrosis.评论：囊性纤维化中重组人脱氧核糖核酸酶的成本
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Consensus conference: practical applications of Pulmozyme. September 22, 1993.
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7
Early treatment with dornase alfa in cystic fibrosis: what are the issues?囊性纤维化患者早期使用重组人脱氧核糖核酸酶治疗：存在哪些问题？
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[Cystic fibrosis. Current indications for nebulized treatments: antibiotics and DNase].[囊性纤维化。雾化治疗的当前适应证：抗生素和脱氧核糖核酸酶]
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本文引用的文献

1
Liquefaction of viscous purulent exudates by deoxyribonuclease.脱氧核糖核酸酶对粘性脓性渗出物的液化作用。
Lancet. 1950 Dec 9;2(6641):739-42. doi: 10.1016/s0140-6736(50)91676-x.
2
Composition of tracheobronchial secretions in cystic fibrosis of the pancreas and bronchiectasis.胰腺囊性纤维化和支气管扩张时气管支气管分泌物的成分
Pediatrics. 1959 Nov;24:739-45.
3
In-vitro evaluation of effect of enzymes on tracheobronchial secretions from patients withcystic fibrosis.酶对囊性纤维化患者气管支气管分泌物影响的体外评估
Pediatrics. 1961 Apr;27:589-96.
4
Efficacy and safety of short-term administration of aerosolised recombinant human DNase I in adults with stable stage cystic fibrosis.雾化吸入重组人脱氧核糖核酸酶I短期治疗稳定期成人囊性纤维化的疗效和安全性。
Lancet. 1993 Jul 24;342(8865):199-202. doi: 10.1016/0140-6736(93)92297-7.
5
Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. The Pulmozyme Study Group.雾化重组人脱氧核糖核酸酶对囊性纤维化患者呼吸道症状加重及肺功能的影响。Pulmozyme研究组。
N Engl J Med. 1994 Sep 8;331(10):637-42. doi: 10.1056/NEJM199409083311003.
6
Within-subject variability and per cent change for significance of spirometry in normal subjects and in patients with cystic fibrosis.
Am Rev Respir Dis. 1980 Dec;122(6):859-66. doi: 10.1164/arrd.1980.122.6.859.
7
Dornase aerosol effect on sputum viscosity in cases of cystic fibrosis.多纳酶气雾剂对囊性纤维化患者痰液黏稠度的影响。
JAMA. 1968 Jul 29;205(5):312-3.
8
Bronchospasm after inhalation of pancreatic dornase.
Am Rev Respir Dis. 1968 Oct;98(4):697-8. doi: 10.1164/arrd.1968.98.4.697.
9
Variability of pulmonary function tests in cystic fibrosis.囊性纤维化患者肺功能测试的变异性
Pediatr Pulmonol. 1990;8(1):16-22. doi: 10.1002/ppul.1950080107.
10
Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum.重组人脱氧核糖核酸酶I降低囊性纤维化痰液的黏稠度。
Proc Natl Acad Sci U S A. 1990 Dec;87(23):9188-92. doi: 10.1073/pnas.87.23.9188.