Fagerström K O, Tönnesen P
Pharmacia Forschungsabteilung, Helsingborg, Sweden.
Wien Med Wochenschr. 1995;145(4):77-82.
The nicotine gum is a flexible dosing form that allows for self-titration of nicotine. In order to secure adequate use instructions and guidance are necessary. The patches are fixed dose systems with no possibility to adjust dose, generally or momentarily. Because of its convenience to use, patch may be the first choice in a general practice setting while gum may prove more effective in a cessation clinic setting where more time and experience is available. Using both patch and gum in combination a certain base level of nicotine is established with patch, often insufficient in itself, but with adding of gum the desire for smoking will be better controlled.
尼古丁口香糖是一种灵活的给药形式，可实现尼古丁的自我滴定。为确保正确使用，需要有充分的使用说明和指导。贴片是固定剂量系统，一般情况下或临时都无法调整剂量。由于使用方便，贴片可能是全科医疗环境中的首选，而口香糖在有更多时间和经验的戒烟诊所环境中可能更有效。同时使用贴片和口香糖，贴片可建立一定的尼古丁基础水平，其本身往往不足，但加上口香糖后，对吸烟的欲望将得到更好的控制。
