Huang J L, Lin T Y, Wang K F
Department of Pediatrics, Chang Gung Memorial Hospital, Taipei, Taiwan, R.O.C.
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1995 Jan-Feb;36(1):20-3.
Sinus disease has been assumed to exist in children with respiratory tract allergies. We consecutively evaluated 375 patients (245 male, 130 female) with childhood onset asthma, between 5 and 15 years of age (mean 7.8 years of age). Abnormal Waters radiographs were found in 205 patients (54.7%) which included mucosal wall thickening greater than 6 mm (67.3%), complete opacification (22.9%) and air-fluid levels (9.8%). The level of immunoglobulin (Ig) E was found to be much higher in non-sinusitis asthmatic children than in asthmatic children with sinusitis (1207 IU/mL vs. 644 IU/mL). The IgG, IgA, IgM and erythrocyte sedimentation rate (ESR) values were not significantly different in the two groups. All patients were treated with antibiotics for 3 to 6 weeks. Five patients required surgical intervention after antibiotic treatment had little success. Streptococcus viridans was isolated from 4 patients following surgical aspirates and Peptostreptococcus anaerobius was isolated in only one patient. In conclusion, sinusitis in children may be an aggravating factor for chronic reactive lower airway disease. Optimal treatment may decrease the need of asthmatic medication.
呼吸道过敏的儿童被认为存在鼻窦疾病。我们连续评估了375例5至15岁（平均7.8岁）儿童期起病的哮喘患者（245例男性，130例女性）。在205例患者（54.7%）中发现华氏位X线片异常，包括黏膜壁增厚超过6毫米（67.3%）、完全混浊（22.9%）和气液平面（9.8%）。发现非鼻窦炎哮喘儿童的免疫球蛋白（Ig）E水平远高于鼻窦炎哮喘儿童（1207 IU/mL对644 IU/mL）。两组的IgG、IgA、IgM和红细胞沉降率（ESR）值无显著差异。所有患者均接受了3至6周的抗生素治疗。5例患者在抗生素治疗效果不佳后需要手术干预。手术抽吸后从4例患者中分离出草绿色链球菌，仅1例患者分离出厌氧消化链球菌。总之，儿童鼻窦炎可能是慢性反应性下气道疾病的一个加重因素。最佳治疗可能会减少哮喘药物的需求。
