Businco L, Fiore L, Frediani T, Artuso A, Di Fazio A, Bellioni P
Int J Pediatr Otorhinolaryngol. 1981 Dec;3(4):287-94. doi: 10.1016/0165-5876(81)90053-7.
Eighty children between 4 and 14 years of age suffering from bronchial asthma were investigated. Fifty-five of them showed clinical and radiological findings of sinusitis. Of these, 13 patients with purulent postnasal drip were treated with ampicillin, phenylephrine and triprolidine (therapy A) and for the other 42 ampicillin was replaced by beclomethasone (therapy B). Thirty-four of 55 children showed improvement in sinus X-rays; 20 children had a considerable decrease in the severity of asthma and many symptoms cleared up after the therapy for sinusitis (P less than 0.001). In conclusion, owing to the high prevalence of sinusitis in children with bronchial asthma, all asthmatic children should be investigated to check for a sinus disease.
对80名4至14岁患有支气管哮喘的儿童进行了调查。其中55名有鼻窦炎的临床和放射学表现。在这些患者中，13例脓性鼻后滴漏患者接受了氨苄西林、去氧肾上腺素和曲普利啶治疗（疗法A），另外42例患者将氨苄西林换成了倍氯米松（疗法B）。55名儿童中有34名鼻窦X光片显示有所改善；20名儿童哮喘严重程度大幅降低，鼻窦炎治疗后许多症状消失（P<0.001）。总之，由于支气管哮喘儿童鼻窦炎的高患病率，所有哮喘儿童都应接受检查以排查鼻窦疾病。
