血管造影显示光滑的左前降支冠状动脉对乙酰胆碱血管反应受损的易感性增加，以及血管反应受损与低密度脂蛋白胆固醇水平之间的关系。
Increased susceptibility of angiographically smooth left anterior descending coronary artery to an impairment of vasoresponse to acetylcholine, and the relation between impaired vasoresponse and low-density lipoprotein cholesterol level.
作者信息
Kawashima T, Yashiro A, Nandate H, Himeno E, Oka Y, Kaku T, Nakashima Y, Kuroiwa A
机构信息
Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan, School of Medicine, Kitakyushu.
出版信息
Am J Cardiol. 1995 Jun 15;75(17):1265-7. doi: 10.1016/s0002-9149(99)80775-9.
PMID:7778552
Abstract
In the present study, we demonstrated that the angiographically smooth LAD is more susceptible than the LC to an impairment of vasoresponse to acetylcholine, suggesting the more severe endothelial dysfunction in the LAD. We also showed that levels of LDL play a partial but important role on endothelial dysfunction.
摘要
在本研究中，我们证明，在血管造影上表现平滑的左前降支（LAD）比回旋支（LC）对乙酰胆碱血管反应受损更敏感，提示左前降支存在更严重的内皮功能障碍。我们还表明，低密度脂蛋白（LDL）水平在内皮功能障碍中起部分但重要的作用。
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