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冠状动脉粥样硬化扩展与危险因素及视网膜动脉变化的对比研究

[Comparative study of the extension of coronary arteriosclerosis with risk factors and changes in the retinal artery].

作者信息

Manfroi W C, Lavinski J, Ferreira R da C, Chotgues L F, de Quadros A S, Maestri T D, Betat R, Campos M, Schmidt M

机构信息

Hospital de Clínicas da Faculdade de Medicina da UFRS, Porto Alegre.

出版信息

Arq Bras Cardiol. 1994 Sep;63(3):185-9.

PMID:7778989
Abstract

PURPOSE

To identify a possible relationship of the extent of coronary artery disease, with risk factors for coronary artery disease and the retinal arteriolar changes (evaluated by fundoscopic examination).

METHODS

We studied 96 patients (66 males), 36 to 72 years of age. All patients were studied by selective cinecoronaryarteriography, fundoscopic examination, as well as evaluated for the common risk factors, cigarette smoking diabetes, dislipidemia, systemic hypertension, age, alcoholism, male sex, family history and obesity.

RESULTS

Male (p < 0.001) and smoking (p < 0.01) were the statistically significant associations with the extent of coronary artery disease. No significant relationship with the extent of coronary artery disease was present for the other risk factor nor for changes in retinal arteriolar branches.

CONCLUSION

A relationship between extent of coronary artery disease with male sex and a cigarette smoker is occurred. No relationship with other risk factors, nor with retinal arteriolar changes were present.

摘要

目的

确定冠状动脉疾病的严重程度与冠状动脉疾病危险因素及视网膜小动脉变化(通过眼底检查评估)之间可能存在的关系。

方法

我们研究了96例患者(66例男性),年龄在36至72岁之间。所有患者均接受了选择性冠状动脉造影、眼底检查,并评估了常见危险因素,包括吸烟、糖尿病、血脂异常、系统性高血压、年龄、酗酒、男性性别、家族史和肥胖。

结果

男性(p < 0.001)和吸烟(p < 0.01)与冠状动脉疾病的严重程度在统计学上存在显著关联。其他危险因素以及视网膜小动脉分支的变化与冠状动脉疾病的严重程度均无显著关系。

结论

冠状动脉疾病的严重程度与男性性别和吸烟者之间存在关联。与其他危险因素以及视网膜小动脉变化均无关系。

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Arq Bras Cardiol. 1994 Sep;63(3):185-9.
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The relationship between retinal microvascular abnormalities and coronary heart disease: a review.视网膜微血管异常与冠心病的关系:综述。
Am J Med. 2010 Apr;123(4):374.e1-7. doi: 10.1016/j.amjmed.2009.05.030.