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Hibernating myocardium represents a primary downregulation of regional myocardial oxygen consumption distal to a critical coronary stenosis.

作者信息

Canty J M, Fallavollita J A

机构信息

State University of New York at Buffalo 14215, USA.

出版信息

Basic Res Cardiol. 1995 Jan-Feb;90(1):5-8. doi: 10.1007/BF00795106.

DOI:10.1007/BF00795106
PMID:7779061
Abstract
摘要

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Blood flow, flow reserve, and glucose utilization in viable and nonviable myocardium in patients with ischemic cardiomyopathy.缺血性心肌病患者存活和非存活心肌中的血流、血流储备和葡萄糖利用率。
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Long-term preservation of myocardial energetic in chronic hibernating myocardium.慢性冬眠心肌中心肌能量的长期保存。
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本文引用的文献

1
Mechanisms of chronic regional postischemic dysfunction in humans. New insights from the study of noninfarcted collateral-dependent myocardium.人类慢性局部缺血后功能障碍的机制。对非梗死性侧支循环依赖心肌研究的新见解。
Circulation. 1993 May;87(5):1513-23. doi: 10.1161/01.cir.87.5.1513.
2
Enhanced gene expression of calcium regulatory proteins in stunned porcine myocardium.猪心肌顿抑中钙调节蛋白的基因表达增强。
Cardiovasc Res. 1993 Nov;27(11):2037-43. doi: 10.1093/cvr/27.11.2037.
3
Adaptive responses of coronary circulation and myocardium to chronic reduction in perfusion pressure and flow.
慢性冬眠与慢性心肌顿抑：一个连续统一体。
J Nucl Cardiol. 2000 Sep-Oct;7(5):509-27. doi: 10.1067/mnc.2000.109683.
冠状动脉循环和心肌对灌注压和血流量长期降低的适应性反应。
Am J Physiol. 1994 Feb;266(2 Pt 2):H447-57. doi: 10.1152/ajpheart.1994.266.2.H447.
4
Reductions in coronary flow under resting conditions in collateral-dependent myocardium of patients with complete occlusion of the left anterior descending coronary artery.在左前降支冠状动脉完全闭塞的患者中，依赖侧支循环的心肌在静息状态下冠状动脉血流减少。
J Am Coll Cardiol. 1984 Mar;3(3):668-74. doi: 10.1016/s0735-1097(84)80241-7.
5
Reductions in regional myocardial function at rest in conscious dogs with chronically reduced regional coronary artery pressure.在慢性区域性冠状动脉压力降低的清醒犬中，静息时区域性心肌功能的降低。
Circ Res. 1987 Nov;61(5 Pt 2):II107-16.
6
Postischemic recovery in the stunned myocardium after reperfusion in the presence or absence of a flow-limiting coronary artery stenosis.在存在或不存在限流性冠状动脉狭窄的情况下，再灌注后顿抑心肌的缺血后恢复。
Am Heart J. 1988 Aug;116(2 Pt 1):407-20. doi: 10.1016/0002-8703(88)90613-8.
7
Effect of tachycardia on regional function and transmural myocardial perfusion during graded coronary pressure reduction in conscious dogs.清醒犬在分级降低冠状动脉压力期间心动过速对局部功能和透壁心肌灌注的影响。
Circulation. 1990 Nov;82(5):1815-25. doi: 10.1161/01.cir.82.5.1815.
8
Effect of exercise intensity and duration on regional function during and after exercise-induced ischemia.运动强度和持续时间对运动诱发心肌缺血期间及之后局部功能的影响。
Circulation. 1991 Jun;83(6):2029-37. doi: 10.1161/01.cir.83.6.2029.
9
Myocardial perfusion-contraction matching. Implications for coronary heart disease and hibernation.
Circulation. 1991 Mar;83(3):1076-83. doi: 10.1161/01.cir.83.3.1076.
10
Myocardial 'stunning' in man.人类的心肌“顿抑”
Circulation. 1992 Dec;86(6):1671-91. doi: 10.1161/01.cir.86.6.1671.