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[牛异种骨移植在眼眶手术中的应用]

[Bovine heterologous bone graft in orbital surgery].

作者信息

Morax S, Hurbli T, Smida R

机构信息

Service d'Ophtalmologie, Fondation Ophtalmologique A. de Rothschild, Paris.

出版信息

Ann Chir Plast Esthet. 1993 Aug;38(4):445-50.

PMID:7779174
Abstract

Lubboc (T650) is a bovine heterologous bone implant obtained by specific preparation of trabecular of bone. In vitro and in vivo biocompatibility studies have revealed the absence of any cytotoxicity or systemic toxicity. Lubboc has many fields of application, including all bone graft surgical indications. We report our first results concerning the use of this product in orbital surgery either as a filling or contention material or as an apposition material. On all 20 operated patients we did not encounter any intolerance, inflammation or infection. The follow-up is still too short to appreciate the long term integration of this material which has the advantage of being a substitute for autologous bone, avoiding bone graft harvesting.

摘要

Lubboc(T650)是一种通过对骨小梁进行特定制备而获得的牛源异种骨植入物。体外和体内生物相容性研究表明,它不存在任何细胞毒性或全身毒性。Lubboc有许多应用领域,包括所有骨移植手术适应症。我们报告了关于该产品在眼眶手术中用作填充或支撑材料或对位材料的首批结果。在所有20例接受手术的患者中,我们未遇到任何不耐受、炎症或感染情况。随访时间仍然太短,无法评估这种材料的长期整合情况,而这种材料的优点是可替代自体骨,避免了自体骨采集。

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