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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Gooneratne S R, Eason C T, Dickson C J, Fitzgerald H, Wright G

Animal and Veterinary Sciences Group, Lincoln University, Canterbury, New Zealand.

Hum Exp Toxicol. 1995 Feb;14(2):212-6. doi: 10.1177/096032719501400210.

Sodium monofluoroacetate (1080), a vertebrate pesticide used in New Zealand, was administered orally to rabbits at two dose levels (sub-lethal and lethal) to determine how long 1080 would persist in plasma, liver, kidney, and muscle so that the risk of consumption of meat from lethally or sub-lethally poisoned rabbits by non-target species could be assessed. 2. The plasma elimination half-life in rabbits receiving a sub-lethal dose was 1.1 h. Retention of 1080 in tissue was greater in rabbits dosed with a lethal dose than in those that received a sub-lethal dose. Irrespective of the dose level, concentration of 1080 in muscle, kidney, and liver was substantially lower than in the plasma. 3. Poisoning of dogs is possible because of their extreme susceptibility to 1080. Poisoning of birds is less likely. The risk of secondary poisoning is reduced as the concentration of 1080 declines in putrefying carcasses.

一氟乙酸钠（1080）是一种在新西兰使用的脊椎动物杀虫剂，以两种剂量水平（亚致死剂量和致死剂量）口服给予兔子，以确定1080在血浆、肝脏、肾脏和肌肉中会持续多长时间，从而评估非目标物种食用来自致死或亚致死中毒兔子的肉的风险。2. 接受亚致死剂量的兔子血浆消除半衰期为1.1小时。给予致死剂量的兔子组织中1080的残留量高于接受亚致死剂量的兔子。无论剂量水平如何，肌肉、肾脏和肝脏中1080的浓度均显著低于血浆中的浓度。3. 狗因对1080极度敏感而有可能中毒。鸟类中毒的可能性较小。随着1080在腐烂尸体中的浓度下降，二次中毒的风险降低。

Gooneratne S R, Eason C T, Dickson C J, Fitzgerald H, Wright G

Animal and Veterinary Sciences Group, Lincoln University, Canterbury, New Zealand.

Hum Exp Toxicol. 1995 Feb;14(2):212-6. doi: 10.1177/096032719501400210.

Sodium monofluoroacetate (1080), a vertebrate pesticide used in New Zealand, was administered orally to rabbits at two dose levels (sub-lethal and lethal) to determine how long 1080 would persist in plasma, liver, kidney, and muscle so that the risk of consumption of meat from lethally or sub-lethally poisoned rabbits by non-target species could be assessed. 2. The plasma elimination half-life in rabbits receiving a sub-lethal dose was 1.1 h. Retention of 1080 in tissue was greater in rabbits dosed with a lethal dose than in those that received a sub-lethal dose. Irrespective of the dose level, concentration of 1080 in muscle, kidney, and liver was substantially lower than in the plasma. 3. Poisoning of dogs is possible because of their extreme susceptibility to 1080. Poisoning of birds is less likely. The risk of secondary poisoning is reduced as the concentration of 1080 declines in putrefying carcasses.

一氟乙酸钠（1080）是一种在新西兰使用的脊椎动物杀虫剂，以两种剂量水平（亚致死剂量和致死剂量）口服给予兔子，以确定1080在血浆、肝脏、肾脏和肌肉中会持续多长时间，从而评估非目标物种食用来自致死或亚致死中毒兔子的肉的风险。2. 接受亚致死剂量的兔子血浆消除半衰期为1.1小时。给予致死剂量的兔子组织中1080的残留量高于接受亚致死剂量的兔子。无论剂量水平如何，肌肉、肾脏和肝脏中1080的浓度均显著低于血浆中的浓度。3. 狗因对1080极度敏感而有可能中毒。鸟类中毒的可能性较小。随着1080在腐烂尸体中的浓度下降，二次中毒的风险降低。