Wu Y W, Seto H, Shimizu M, Kageyama M, Watanabe N, Kakishita M
Department of Radiology, Toyama Medical and Pharmaceutical University, Japan.
Ann Nucl Med. 1995 Feb;9(1):29-32. doi: 10.1007/BF03165005.
A patient with osteomalacia secondary to vitamin D deficiency after gastrectomy for gastric cancer is presented. Initial bone scintigrams showed both asymmetric and symmetric focal areas of intense uptake due to pseudofractures reminiscent of bone metastases. Radiographs only confirmed the presence of pseudofractures at some, but not all, of the abnormal sites demonstrated by bone scintigraphy. At first, metastatic bone disease was suspected. However, the appearance of repeated bone scintigram was normalized after treatment with vitamin D. A diagnosis of osteomalacia was established. The present case serves to illustrate that symmetric focal lesions are important features of pseudofractures secondary to osteomalacia, and comparison with radiographs and repeated bone scintigraphy are necessary in distinguishing between bone metastases and pseudofractures.
本文报告了一例胃癌胃切除术后因维生素D缺乏继发骨软化症的患者。最初的骨扫描显示,由于假骨折,出现了不对称和对称的局灶性浓聚区,类似于骨转移。X线片仅证实了骨扫描显示的部分而非全部异常部位存在假骨折。起初,怀疑为骨转移瘤。然而,维生素D治疗后,重复骨扫描的表现恢复正常。最终确诊为骨软化症。本病例表明,对称的局灶性病变是骨软化症继发假骨折的重要特征,在鉴别骨转移瘤和假骨折时,与X线片及重复骨扫描结果进行对比是必要的。