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Individualisation of HIV therapy: the clinician's perspective.

作者信息

Gazzard B G, Moyle G J

机构信息

Chelsea and Westminster Hospital, London.

出版信息

Br J Clin Pract. 1995 May-Jun;49(3):145-7.

PMID:7779666
Abstract

Assessment of clinical and laboratory markers of HIV infection may be used to individualise antiretroviral therapy. Data suggest that measures of viral load may be of considerable value as both a baseline and dynamic therapy marker, making these tools particularly useful in driving therapeutic decisions. Similarly, in-vitro data regarding intracellular pharmacokinetics and activity, resistance patterns and potential synergy of antiretroviral agents may be used to guide selection of optimal treatment regimens in clinical practice.

摘要

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Use of viral resistance patterns to antiretroviral drugs in optimising selection of drug combinations and sequences.
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