使用发色底物评估血浆纤维蛋白溶解系统。
Assessment of plasma fibrinolytic system with use of chromogenic substrate.
作者信息
Latallo Z S, Teisseyre E, Lopaciuk S
出版信息
Haemostasis. 1978;7(2-3):150-4. doi: 10.1159/000214254.
PMID:77806
Abstract
A block of tests employing a chromogenic substrate H-D-Val-Leu-Lys-pNA (S-2251, Kabi AB, Stockholm) is proposed for a quantitative assessment of the plasma fibrinolytic system. It allows measurement of spontaneous plasmin activity, plasminogen content, activator activity (ability of plasma to activate plasminogen), immediate and progressive antiplasmin levels and alpha2-macroglobulin. All these assays could be performed within 45 min using a total of 0.4 ml of plasmin.
摘要
有人提出采用发色底物H-D-缬氨酸-亮氨酸-赖氨酸-对硝基苯胺（S-2251，瑞典斯德哥尔摩卡比公司）进行一组检测，用于定量评估血浆纤维蛋白溶解系统。它能够测量自发纤溶酶活性、纤溶酶原含量、激活剂活性（血浆激活纤溶酶原的能力）、即时和进行性抗纤溶酶水平以及α2-巨球蛋白。使用总共0.4毫升血浆，所有这些检测均可在45分钟内完成。
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