磁共振弛豫测量法：评估肾衰竭中的水合过多情况。

MR relaxometry: estimating overhydration in renal failure.

作者信息

Sievers K W, Löhr E, Bauermann T

机构信息

Department of Radiology, University of Essen, Germany.

出版信息

Comput Med Imaging Graph. 1995 Mar-Apr;19(2):219-26. doi: 10.1016/0895-6111(95)00001-7.

DOI:10.1016/0895-6111(95)00001-7

PMID:7780947

Abstract

An MR method is described for estimating overhydration in patients suffering from renal failure. In 29 healthy volunteers, the fat content of a selected slice of the lower limb was correlated to the overall T1-relaxation time (r = -0.97, p < 0.000001). When compared with the normal T1 of the voluntary group, delta T1 was calculated having regard to the individual fat content in 74 MR studies of 22 overhydrated patients. MR results were correlated with the difference between clinically estimated dry and the actual body weight (r = 0.6, p < 0.000001). In an intraindividual follow-up (11 studies) MRI was shown to provide good correlation to the actual body weight (r = 0.9, p < 0.0005) and fluid balance (r = 0.87, p < 0.001).

摘要

描述了一种用于估计肾衰竭患者水合过多情况的磁共振成像（MR）方法。在29名健康志愿者中，选定下肢切片的脂肪含量与总体T1弛豫时间相关（r = -0.97，p < 0.000001）。在对22名水合过多患者进行的74项MR研究中，根据个体脂肪含量计算出δT1，并与自愿组的正常T1进行比较。MR结果与临床估计的干体重和实际体重之间的差异相关（r = 0.6，p < 0.000001）。在个体随访（11项研究）中，磁共振成像显示与实际体重（r = 0.9，p < 0.0005）和液体平衡（r = 0.87，p < 0.001）具有良好的相关性。