Izumi T, Kusaka H, Imai T
Department of Neurology, Kitano Hospital.
Rinsho Shinkeigaku. 1995 Jan;35(1):38-43.
A 26-year-old male patient gradually developed muscular atrophy of the right lower leg over a two-year period. Neurological examination revealed absent Achilles tendon reflex and muscular atrophy of the right lower leg and right hamstring muscles. Conduction velocity of the F waves was delayed in the right posterior tibial nerve. A computerized tomography scan and magnetic resonance imaging revealed a mass lesion along the proximal segment of the right sciatic nerve. Exploration revealed a fusiformly swollen sciatic nerve. Histological examination showed that a swollen segment of the sciatic nerve was filled with onion-bulb formations of perineurial cells, consistent with the diagnosis of localized hypertrophic neuropathy. This condition should be added to several etiologies of monomelic amyotrophy. Electrophysiological studies and neuroimaging techniques were useful in obtaining differential diagnosis.
一名26岁男性患者在两年时间里逐渐出现右小腿肌肉萎缩。神经学检查显示跟腱反射消失，右小腿和右腘绳肌肌肉萎缩。右侧胫后神经F波传导速度延迟。计算机断层扫描和磁共振成像显示右侧坐骨神经近端有一个肿块病变。探查发现坐骨神经呈梭形肿胀。组织学检查显示坐骨神经的一个肿胀节段充满了神经束膜细胞的洋葱球样结构，符合局限性肥厚性神经病的诊断。这种情况应被列入单肢肌萎缩的几种病因之中。电生理研究和神经影像学技术有助于进行鉴别诊断。
