Slot W B, van Kasteel V, Coerkamp E G, Seelen P J, van der Werf S D
Department of Medicine, Westeinde Hospital, The Hague, The Netherlands.
Dig Dis Sci. 1995 Jun;40(6):1395-9. doi: 10.1007/BF02065558.
This report describes a 33-year-old female patient who presented with severe neurological symptoms and signs during postpartum relapse of Crohn's ileocolitis. The cause of the neurological deficit was extensive major vessel thrombosis resulting in spinal cord ischemia. Etiologic factors involved in this exceptional thrombotic state are discussed with emphasis on the relationship between low levels of folic acid, homocysteine metabolism, and coagulation.
本报告描述了一名33岁女性患者,她在克罗恩病回结肠炎症产后复发期间出现了严重的神经症状和体征。神经功能缺损的原因是广泛的大血管血栓形成导致脊髓缺血。本文讨论了这种特殊血栓形成状态所涉及的病因学因素,重点是低叶酸水平、同型半胱氨酸代谢和凝血之间的关系。