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激素替代疗法:骨质疏松症筛查后的依从性与成本

Hormone replacement therapy: compliance and cost after screening for osteoporosis.

作者信息

Torgerson D J, Donaldson C, Russell I T, Reid D M

机构信息

Health Economics Research Unit, University of Aberdeen, Foresterhill, Scotland, UK.

出版信息

Eur J Obstet Gynecol Reprod Biol. 1995 Mar;59(1):57-60. doi: 10.1016/0028-2243(94)02002-v.

Abstract

OBJECTIVE

To assess HRT compliance and cost 1 year after population screening for low bone density.

DESIGN

Postal questionnaire sent out to women 1 year after having a bone density scan.

MAIN OUTCOME MEASURES

Compliance with HRT, type of HRT and cost.

RESULTS

Compliance with HRT after screening for women with low bone density was 48% for postmenopausal women and 59% for women with a simple hysterectomy. The most often used form of HRT was Estraderm (49%) for women with a hysterectomy, whilst for women with an intact uterus Prempak-C (54%) was the most popular. The average annual cost of treating women who had had a hysterectomy was 67 pounds whilst for women with an intact uterus it was 61 pounds, a non-significant difference.

CONCLUSIONS

Approximately 50% of women with low bone density had started HRT within 1 year of having a densitometry examination. Previous reports of the cost advantage of treating women who had had a hysterectomy relative to those who had not has been overstated.

摘要

目的

评估在对人群进行低骨密度筛查1年后激素替代疗法(HRT)的依从性及费用情况。

设计

在女性进行骨密度扫描1年后向其发送邮政调查问卷。

主要观察指标

HRT的依从性、HRT的类型及费用。

结果

对于绝经后女性,低骨密度筛查后HRT的依从性为48%;对于单纯子宫切除术后女性,该依从性为59%。子宫切除术后女性最常使用的HRT剂型为雌二醇透皮贴剂(49%),而子宫未切除的女性中最常用的是倍美盈(54%)。子宫切除术后女性的年均治疗费用为67英镑,子宫未切除女性为61英镑,差异无统计学意义。

结论

约50%的低骨密度女性在进行骨密度检查1年内开始了HRT治疗。既往关于子宫切除术后女性相对于未切除女性治疗费用优势的报道被夸大了。

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