Kraus A, Valencia X, Cabral A R, de la Vega G
Department of Immunology and Rheumatology, Instituto Nacional de la Nutrición Salvador Zubirán, Mexico City, Mexico.
J Rheumatol. 1995 Mar;22(3):497-500.
To report rheumatologic or rheumatologic-like manifestations of the visceral larva migrans (VLM) syndrome.
We carried out a prospective study of patients with VLM seen in a private practice setting in Mexico City between 1990 and 1993.
From a population of 600 patients we identified 6 patients (5 women) with VLM. Three patients complained of arthralgia; in 4 a history of migratory cutaneous lesions was elicited, and in one monoarthritis of the right knee was found. One patient had deep edema that suggested thrombophlebitis of the right arm; the man in our series had right testicular swelling during followup. In 2 cases, panniculitis was documented by biopsy and in one, small vessel vasculitis. Four patients had frequent contact with dogs and one with cats; 4 patients frequently ate raw fish. The diagnosis of VLM was confirmed either by the clinical picture, biopsy, or ELISA:
The spectrum of rheumatological manifestations in VLM may be wider than previously thought.
报告内脏幼虫移行症(VLM)综合征的风湿病学或类似风湿病学表现。
我们对1990年至1993年在墨西哥城一家私人诊所就诊的VLM患者进行了一项前瞻性研究。
在600名患者中,我们确定了6例(5名女性)VLM患者。3例患者主诉关节痛;4例有游走性皮肤病变病史,1例发现右膝单关节炎。1例患者有深部水肿,提示右臂血栓性静脉炎;我们系列中的该男性患者在随访期间右睾丸肿胀。2例经活检证实为脂膜炎,1例为小血管血管炎。4例患者经常接触狗,1例经常接触猫;4例患者经常食用生鱼。VLM的诊断通过临床表现、活检或酶联免疫吸附测定(ELISA)得以证实。
VLM的风湿病学表现范围可能比以前认为的更广。