Lund-Tønnesen S
Infeksjonsseksjonen Medisinsk avdeling, Haukeland Sykehus 5021, Bergen.
Tidsskr Nor Laegeforen. 1996 Sep 20;116(22):2660-1.
Toxocariasis is a cosmopolitan infection of dogs and cats with a roundworm resembling Ascaris. Man becomes infected by ingesting eggs from the environment. The infection occurs mainly in children. There are two distinct syndromes: visceral larva migrans and ocular toxocariasis. The author describes the case of a 70 year old Norwegian female with visceral larva migrans. One month after a visit to Spain she developed fever, hepatomegaly and marked eosinophilia. Liver biopsy revealed subacute hepatitis with eosinophilic leucocyte infiltration. Toxocara ELISA was strongly positive. Treatment with albendazol 400 mg b.i.d. and prednisone 10 mg daily for three weeks was successful. A clinical relapse after three months was treated in the same way for one month. Prolonged treatment is recommended. To our knowledge, this is the first reported case of visceral larva migrans in an adult Norwegian. Epidemiology, diagnosis and treatment are discussed.
弓蛔虫病是一种在狗和猫中普遍存在的由一种类似蛔虫的圆虫引起的感染。人类通过摄入环境中的虫卵而感染。这种感染主要发生在儿童身上。有两种不同的综合征:内脏幼虫移行症和眼弓蛔虫病。作者描述了一名70岁挪威女性患内脏幼虫移行症的病例。在访问西班牙一个月后,她出现发热、肝肿大和明显的嗜酸性粒细胞增多。肝脏活检显示亚急性肝炎伴嗜酸性白细胞浸润。弓蛔虫酶联免疫吸附测定呈强阳性。给予阿苯达唑400毫克每日两次和泼尼松10毫克每日一次,持续三周,治疗成功。三个月后临床复发,以同样方式治疗一个月。建议进行长期治疗。据我们所知,这是挪威成年人中首例报告的内脏幼虫移行症病例。文中讨论了其流行病学、诊断和治疗。