Perez-Ruiz F, Calabozo M, Alonso-Ruiz A, Herrero A, Ruiz-Lucea E, Otermin I
Rheumatology Section, Hospital de Cruces, Vizcaya, Pais Vasco, Spain.
J Rheumatol. 1995 Mar;22(3):501-4.
To assess the prevalence of carpal tunnel syndrome (CTS) in patients with fibromyalgia syndrome (FM).
A series of 206 consecutive patients with FM was evaluated for CTS in an unblinded, uncontrolled study. Sixty patients with dermatomal paresthesia in the fingers enervated by the median nerve were evaluated with electromyogram and nerve conduction velocity studies (EMG/NCV).
Thirty-three patients showed EMG/NCV findings diagnostic for CTS (16% of the 206 cases, 55% of the 60 EMG studies). Only 2 of the 33 patients with CTS had been diagnosed before rheumatologic evaluation. We compared our results with those reported for women in the general population. The overall prevalence of CTS in women was higher (16 vs 10.2%), but not statistically different. However, in our series, there was a clear difference in the higher rate of undetected CTS in women with FM compared to that of the general population (14.1 vs 6.7%) (p < 0.01).
(1) CTS is at least as common in patients with FM as in the general population, contrary to that reported in retrospective studies; (2) the rate of underdiagnosed CTS in women with FM is much higher than the rate reported in the general population; (3) NCV studies may be necessary to evaluate underdiagnosed CTS in patients with FM and dermatomal paresthesia in their hands.
评估纤维肌痛综合征（FM）患者中腕管综合征（CTS）的患病率。
在一项非盲、非对照研究中，对连续的206例FM患者进行了CTS评估。对60例由正中神经支配手指出现皮节性感觉异常的患者进行了肌电图和神经传导速度研究（EMG/NCV）。
33例患者的EMG/NCV结果诊断为CTS（206例中的16%，60例EMG研究中的55%）。33例CTS患者中只有2例在风湿科评估前被诊断出来。我们将我们的结果与普通人群中女性的报告结果进行了比较。女性CTS的总体患病率更高（16%对10.2%），但无统计学差异。然而，在我们的系列研究中，FM女性患者中未被发现的CTS发生率与普通人群相比有明显差异（14.1%对6.7%）（p<0.01）。
（1）与回顾性研究报告的情况相反，CTS在FM患者中的常见程度至少与普通人群相同；（2）FM女性患者中CTS诊断不足的发生率远高于普通人群报告的发生率；（3）对于FM患者且手部有皮节性感觉异常的情况，可能需要进行NCV研究以评估未被诊断的CTS。
