田鼠（小家鼠）和小林姬鼠体内的胎盘催乳素（绒毛膜促乳腺素）

Placental lactogen (chorionic mammotrophin) in the field vole, Microtus agrestis, and the bank vole, Clethrionomys glareolus.

作者信息

Forsyth I A, Blake L A

出版信息

J Endocrinol. 1976 Jul;70(1):19-23. doi: 10.1677/joe.0.0700019.

DOI:10.1677/joe.0.0700019

Abstract

Placental lactogen has been detected in the field vole, Microtus agrestis, and the bank vole, Clethrionomys glareolus, using a co-culture technique. In field voles this activity could be detected from about day 8 of pregnancy to shortly before term, and stimulated both mouse and vole mammary gland to secrete in vitro. Partial immunological cross-reaction was detected in a radioimmunoassay system between rat prolactin and either extracts of vole pituitaries or media on which vole pituitaries had been cultured; vole placental lactogen showed no cross-reaction with rat prolactin. One site of origin for this hormone is probably the trophoblastic giant cells.

摘要

利用共培养技术，在田鼠（Microtus agrestis）和林姬鼠（Clethrionomys glareolus）中检测到了胎盘催乳素。在田鼠中，这种活性从怀孕约第8天到足月前不久都能检测到，并且在体外能刺激小鼠和田鼠的乳腺分泌。在放射免疫分析系统中，大鼠催乳素与田鼠垂体提取物或培养过田鼠垂体的培养基之间检测到部分免疫交叉反应；田鼠胎盘催乳素与大鼠催乳素没有交叉反应。这种激素的一个起源部位可能是滋养层巨细胞。