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搜索tRNA序列与氨酰tRNA合成酶家族的相关性。

Searching tRNA sequences for relatedness to aminoacyl-tRNA synthetase families.

作者信息

Nicholas H B, McClain W H

机构信息

Pittsburgh Supercomputing Center, PA 15213-2683, USA.

出版信息

J Mol Evol. 1995 May;40(5):482-6. doi: 10.1007/BF00166616.

DOI:10.1007/BF00166616
PMID:7783223
Abstract

tRNA sequences were analyzed for sequence features correlated with known classes of aminoacyl-tRNA synthetase enzymes. The tRNAs were searched for distinguishing nucleotides anywhere in their sequences. The analyses did not find nucleotides predictive of synthetase class membership. We conclude that such nucleotides never existed in tRNA sequences or that they existed and were lost from many of the tRNA sequences during evolution.

摘要

对转运RNA（tRNA）序列进行了分析，以寻找与已知种类的氨酰tRNA合成酶相关的序列特征。在tRNA的整个序列中搜索能够区分它们的核苷酸。分析未发现可预测合成酶种类归属的核苷酸。我们得出结论，此类核苷酸从未存在于tRNA序列中，或者它们曾经存在，但在进化过程中从许多tRNA序列中丢失了。

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Searching tRNA sequences for relatedness to aminoacyl-tRNA synthetase families.搜索tRNA序列与氨酰tRNA合成酶家族的相关性。
J Mol Evol. 1995 May;40(5):482-6. doi: 10.1007/BF00166616.
2
Evolution of the aminoacyl-tRNA synthetases and the origin of the genetic code.氨酰-tRNA合成酶的进化与遗传密码的起源
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