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[一例与鸟分枝杆菌感染相关的嗜酸性粒细胞性肺炎病例]

[A case of eosinophilic pneumonia associated with Mycobacterium avium infection].

作者信息

Suganuma H, Inui N, Sato J, Sato A

机构信息

Department of Respiratory Medicine, Fujieda Shida Municipal Hospital, Japan.

出版信息

Kekkaku. 1995 May;70(5):355-60.

PMID:7783396
Abstract

A 54 year-old woman was admitted with cough and high fever. Computed tomographic scan of the chest showed bilateral patchy infiltrates, predominantly in the upper lobes. Eosinophils in the bronchoalveolar lavage fluid (BALF) accounted for 19% of BALF cells. Furthermore, Mycobacterium avium was isolated from a bronchial washing from the upper area of the right lung (S3) and a sample of sputum which had been submitted for microbial examination about 1 month before admission by another clinic. Based on these finding's the diagnosis of eosinophilic pneumonia associated with Mycobacterium avium infection was established. The infiltrates of the lung rapidly decreased after administration of antituberculous agents. The simultaneous presentation of eosinophilic pneumonia and Mycobacterium avium infection has not been previously reported. Because of the efficacy of antituberculous agents in this case, we concluded that Mycobacterium avium was a cause of eosinophilic pneumonia.

摘要

一名54岁女性因咳嗽和高热入院。胸部计算机断层扫描显示双侧斑片状浸润,主要在上叶。支气管肺泡灌洗液(BALF)中的嗜酸性粒细胞占BALF细胞的19%。此外,从右肺上叶区域(S3)的支气管冲洗液和入院前约1个月由另一家诊所送检微生物检查的痰液样本中分离出鸟分枝杆菌。基于这些发现,确诊为与鸟分枝杆菌感染相关的嗜酸性粒细胞性肺炎。给予抗结核药物后,肺部浸润迅速减轻。嗜酸性粒细胞性肺炎与鸟分枝杆菌感染同时出现此前未见报道。鉴于本例中抗结核药物的疗效,我们得出结论,鸟分枝杆菌是嗜酸性粒细胞性肺炎的病因。

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