Mori K, Yoshikawa M, Nakamura T, Tomoda K, Nakaya M, Fu A, Tokuyama T, Fukuoka K, Yamamoto C, Tsukaguchi K
Second Department of Internal Medicine, Nara Medical University, Japan.
Kekkaku. 1995 Sep;70(9):511-6.
A 46-years-old male was admitted to our hospital because of productive cough and infiltrates on the chest roentogenogram. The patient had a history of left upper bullectomy ten years prior to the admission. The CT scan of the chest on admission showed infiltrats with cavitation in the left apex and multiple bullae in almost whole lung. Microscopical examination of smears of sputum and bronchoalveolar lavage fluid revealed acid-fast bacilli. They were identified as Mycobacterium szulgai by DNA-DNA hybridization method. The patient was treated with isoniazid, streptomycin and rifampicin. After treatment for about a month, the culture of sputum converted to negative for M. szulgai. After about three months hospitalization, the infiltrates decreased and the cavity wall became thin, and no recurrence sign has been observed after the discharge. There are a few case reports of pulmonary infection due to M. szulgai associated with bullous disease of the lung in Japan.
一名46岁男性因咳嗽咳痰及胸部X线片出现浸润影而入院。患者在入院前十年有左上肺大疱切除术史。入院时胸部CT扫描显示左肺尖部有浸润伴空洞形成，几乎整个肺部有多个肺大疱。痰涂片及支气管肺泡灌洗 fluid显微镜检查发现抗酸杆菌。通过DNA-DNA杂交法鉴定为苏尔加分枝杆菌。患者接受异烟肼、链霉素和利福平治疗。治疗约一个月后，痰培养苏尔加分枝杆菌转为阴性。住院约三个月后，浸润影减少，空洞壁变薄，出院后未观察到复发迹象。在日本，有几例关于苏尔加分枝杆菌引起的肺部感染合并肺大疱病的病例报告。
