急性恶性或暴发性脚气性心脏病。6例报告。
Acute pernicious or fulminating beriberi heart disease. A report of 6 patients.
作者信息
ter Maaten J C, Hoorntje S J, Hillen H F
机构信息
Department of Internal Medicine, Catharina Hospital, Eindhoven, Netherlands.
出版信息
Neth J Med. 1995 May;46(5):217-24. doi: 10.1016/0300-2977(95)00003-8.
OBJECTIVE
To investigate the incidence and presentation of acute pernicious or fulminating beriberi in a general district hospital.
METHODS
All patients with a diagnosis of acute pernicious or fulminating beriberi heart disease made between 1978 and 1994 were identified, and their medical records were retrospectively examined.
RESULTS
Six cases of acute pernicious or fulminating beriberi heart disease were recognized. The disease was characterized by circulatory shock and peripheral cyanosis. All patients had severe lactic acidosis, in 5 of them without hypoxaemia. Four patients were alcoholics. The most important diagnostic criterion was the impressive improvement after thiamine administration.
CONCLUSIONS
Acute pernicious or fulminating beriberi heart disease can be recognized occasionally. Thiamine should be administered as soon as possible in suspected cases.
目的
调查一家普通地区医院中急性恶性或暴发性脚气病的发病率及表现。
方法
确定1978年至1994年间所有诊断为急性恶性或暴发性脚气病心脏病的患者，并对其病历进行回顾性检查。
结果
确诊6例急性恶性或暴发性脚气病心脏病。该病的特征为循环性休克和外周发绀。所有患者均有严重乳酸酸中毒，其中5例无低氧血症。4例患者为酗酒者。最重要的诊断标准是给予硫胺素后病情显著改善。
结论
急性恶性或暴发性脚气病心脏病偶尔可被识别。疑似病例应尽快给予硫胺素。
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